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The Principles of Clinical Cytogenetics

This thoroughly revised and expanded edition of a highly praised classic, The Principles of Clinical Cytogenetics, includes the many advances that have occurred in the field. Among the highlights are a full section devoted to advances in fluorescence in situ hybridization (FISH) technology, increased coverage of cancer cytogenetics-both hematopoietic neoplasms and tumor cytogenetics-and new chapters on chromosome instability and the cytogenetics of infertility. The book offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, and cytogeneticists the clear understanding they need to carry out and interpret their test results rapidly.

To facilitate the exchange of gases, the tops or caps of tissue culture vessels are
loosely applied. A CO2 incubator is required for open systems to maintain the 5%
CO2 level necessary to sustain the ideal pH of 7.2–7.4. A humidity level of 97% ...